翻訳と辞書
Words near each other
・ Sequential consistency
・ Sequential coupling
・ Sequential decoding
・ Sequential dynamical system
・ Sequential equilibrium
・ Sequential estimation
・ Sequential euclidean distance transforms
・ Sequential function chart
・ Sequential game
・ Sequential hermaphroditism
・ Sequential high-dose chemotherapy
・ Sequential lineups
・ Sequential logic
・ Sequential manual transmission
・ Sequential minimal optimization
Sequential model
・ Sequential pattern mining
・ Sequential probability ratio test
・ Sequential proportional approval voting
・ Sequential quadratic programming
・ Sequential receivers
・ Sequential space
・ Sequential structure alignment program
・ Sequential system
・ Sequential time
・ Sequential transmission
・ Sequential walking
・ Sequentially compact space
・ Sequenza
・ Sequenza I


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Sequential model : ウィキペディア英語版
Sequential model

The sequential model (also known as the KNF model ) is a theory that describes co-operativity of protein subunits.
==Overview==
This model for allosteric regulation of enzymes suggests that the subunits of multimeric proteins have two conformational states. The binding of the ligand causes conformational change. Although the subunits go through conformational changes independently (as opposed to in the MWC model) the switch of one subunit makes the other subunits more likely to change, by reducing the energy needed for subsequent subunits to undergo the same conformational change. In elaboration, the binding of a ligand to one subunit changes the protein's shape, thereby making it more thermodynamically favourable for the other subunits to switch conformation to the high affinity state. It is named KNF after Koshland, Némethy and Filmer.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Sequential model」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.